Corneo-dermato-osseous syndrome (cdo syndrome; corneal dystrophy, epithelial with skin and skeletal changes)   304

General: Autosomal dominant; similar lesions of palms, soles, and cornea occur III Richner-Hanhart syndrome.

Ocular: Epithelial and stromal corneal changes; photophobia; keratoconus.

Clinical: Palmotar hyperkeratosis; brachydactyly, short stature; premature birth; soft teeth.

McKusick VA. Mendelian Inheritance in Man; A Catalog of Human Genes and Genetic Disorders, 12th ed. Baltimore: The Johns Hopkins University Press, 1998.

Online Mendelian Inheritance in Man, OMIM. McKusick-Nathans Institute for Genetic Medicine, Johns Hopkins University and National Center for Biotechnology Information, National Library of Medicine, February 12, 2007. World Wide Web URL: https://www.ncbi.nlm.nih.gov/omim/.

Stern JK, et al. Corneal changes, hyperkeratosis, short stature, brachydactyly, and premature birth: a new autosomal dominant syndrome. Am J Med Genet 1984; 18:67-77.