Diffuse unilateral subacute neuroretinitis syndrome (dusn; unilateral wipeout syndrome; wipeout syndrome)  369

General: Caused by a nematode that is not Toxocara canis, that is, at least two nematodes of different sizes; usually occurs in children or young adults; nematode may remain viable in eye for 3 years or longer.

Ocular: Vitreitis; papillitis; gray-white lesions of retina; optic atrophy; retinal vessel narrowing; diffuse pigment epithelial degeneration; endophthalmitis; nematode in fundus; the pathognomonic finding in DUSN is the presence of a motile intraocular nematode.

Clinical: Weight loss; lack of appetite; cough; fever; pulmonary infiltration; hepatomegaly; leukocytosis; persistent eosinophilia.

Gass JD, Braunstein RA. Further observation concerning the diffuse unilateral subacute neuroretinitis syndrome. Arch Ophthalmol 1983; 101:1689-l697.

Gass JD, et al. Diffuse subacute neuroretinitis. Ophthalmology 1978; 85:521-545.

Gass JDM, Olsen KR. Diffuse unilateral subacute neuroretinitis. In: Ryan SJ, ed. Retina, vol. II, 2nd ed. St. Louis: Mosby, 1994.

Sivalingam A, Godberg RE. Diffuse unilateral subacute neuroretinitis. Arch Ophthalmol 1991; 109:1028.