Dorsal Midbrain Syndrome &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; &nb 747i82h sp; 381
General: Caused by lesions of the posterior commissure located in the dorsal midbrain, pineal tumors, shunt malfunction, or hydrocephalus; less common causes include midbrain hemorrhage or infection, hypoxia, multiple sclerosis, trauma, lipid storage disease, Wilson disease, Whipple disease, syphilis, and tuberculosis.
Ocular: Loss of upward gaze; lid retraction; light-near dissociation; impaired convergence and divergence; convergence-retraction nystagmus.
Clinical: Patients tend to adopt abnormal head postures to fixate or maintain binocularity.
Balch RW, Kurman JM, Yee RD. Dorsal midbrain syndrome: Clinical and oculographic Findings. Neurology 1985; 75: 54-60.
Brazis PW 10 Clinical pearls for dorsal midbrain syndrome. Ophthalmol Times January 2000:9.
Buckley SA, Elston JS. Surgical treatment of supranuclear and internuclear ocular motility disorders. Eye 1997; 11[Pt 3]:377-380.
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