Horner Syndrome (Bernard-Horner Syndrome; Cervical
Sympathetic Paralysis Syndrome; Claude-
Bernard-Horner Syndrome; Horner Oculopupillary Syndrome) 5
General: Paralysis of cervical sympathetic; hypothalamic lesion with first neuron involved or lesion in the pons or cervical portion of cord; syndrome present in Babinski-Nageotte, Cestan-Chenais, Dejerine-Klumpke, Pancoast, Raeder, and Wallenberg syndromes (see Babinski-Nageotte Syndrome; Cestan-Chenais Syndrome; Dejerine-Klumpke Syndrome; Pancoast Syndrome; Raeder Syndrome; Wallenberg Syndrome).
Ocular: Enophthalmos; ptosis or narrowing of palpebral fissure; ocular hypotony; miosis (degree of miosis depends on site of lesion; most pronounced when roots of cranial nerves VII and VIII and first thoracic nerve are involved); hypochromic heterochromia (children more than adults); pupil does not dilate with cocaine.
Clinical: Anhidrosis on ipsilateral side of face and neck; transitory rise in facial temperature; hemifacial atrophy; may result from a variety of conditions, including cluster headache, parasellar neoplasms or aneurysms, internal carotid dissection or occlusion, and Tolosa-Hunt syndrome.
Horner F. Ueber eine Form von Ptosis. Klin Monatsbl Augenheilkd 1869; 7:193.
Sears ML, et at. Homer's syndrome caused by occlusion of the vascular supply to sympathetic ganglia. Am J Ophthalmol 1974; 77:717.
Shaari CM, Scherl MO. Nasal obstruction and Homer's syndrome. Otolaryngol Head Neck Surg 1994; 111:838-840.
Thompson HS, Mensher JH. Adrenergic mydriasis in Homer's syndrome: hydroxyamphetamine test for diagnosis of postganglionic defects. Am J Ophthalmol 1971; 72:472.
Tomsak RL. Ophthalmologic aspects of headache. Med Clin North Am 1991; 75:693-706.
Trachimowicz RA, Conto JE. Evaluation of pupillary disorders. In: Roberts DK, Terry JE, eds. Ocular diseases, 2nd ed. Boston: Butterworth-Heinemann, 1996:204-207.
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