Parinaud oculoglandular syndrome (parinaud conjunctiva-adenitis syndrome; catscratch oculoglandular syndrome; catscratch disease; bartonella henselae)

General: Most frequently seen in children; incubation time 7 to 10 days; caused by small pleomorphic Gram-negative bacillus; good prognosis; affects both sexes; about 90% of patients with this condition have serologic evidence of infection by Rochalimaea henselae.

Ocular: Conjunctivitis; retrotarsal conjunctival granulations; formation of granulomata in anterior segment about 3 mm high and 2 to 6 mm in diameter; inferior fornix usually affected; ulceration common; neuroretinitis; optic neuritis.

Clinical: Tender, red papule at the site of a cat scratch; regional preauricular and cervical lymphadenitis (often only one gland involved); irregular fever for 4 to 5 days and malaise; fever; parotid gland swelling.

Carithers HA. Oculoglandular disease of Parinaud: a manifestation of cat-scratch disease. Am J Dis Child 1978; 132: 1195-l200.

Chrousos Ga, et al. Neuroretinitis in cat scratch disease. J Clin Neuro-Ophthalmol 1990; 10:92-94.

Fraunfelder FT, Roy FH. Current Ocular Therapy, 5th ed. Philadelphia: WB Saunders, 2000.

Golden SE. Hepatosplenic cat-scratch disease associated with elevated anti Rochalimaea antibody titers. Pediatr Infect Dis J 1993; 12:868-871.

Miller NR, ed. Walsh and Hoyts Clinical Neuro-Ophthalmology, vol. 5, part 2, 4th ed. Baltimore: Williams & Wilkins, 1995.

Parinaud H, Galezowski X. Conjonctivite Infectieuse Transmise par les Animaux. Ann Ocul (Brux) 1889; 101:252.

Wear DJ, et al. Cat scratch disease bacilli in the conjunctiva of patients with Parinaud's oculoglandular syndrome. Ophthalmology 1985; 92: 1282-l287.