Passow syndrome (bremer status dysraphicus; status dysraphicus syndrome; syringomyelia; syringobulbia)

General: Congenital nonclosure of the neural tube; familial occurrence or may be sporadic; insidious onset in second to third decade of life.

Ocular: Enophthalmos; ptosis; rotatory nystagmus; heterochromia iridis; anterior uveitis; corneal anesthesia; neuroparalytic keratitis; paralysis of third, fifth, sixth, and seventh cranial nerves; Horner syndrome; anisocoria; papilledema; optic atrophy; zonular cataract (see Horner Syndrome).

Clinical: Anesthesia over area of first division of trigeminal nerve; facial hemiatrophy; facial nerve paralysis; muscular weakness; cervical ribs; kyphoscoliosis; spina bifida; unilateral numbness of fingers; loss of deep reflexes; insensitivity to pain and temperature in affected areas; neurogenic bladder.

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