Simmonds Syndrome (Hypopituitarism Syndrome)
General: Anterior pituitary glan 626b18g d destroyed by various causes, such as hemorrhage, infarction, injuries, or postparturition infections; females; late form of Simmonds syndrome is Snapper-Witts with achlorhydria and subacute combined degeneration, and hypochromic or hyperchromic anemia; onset during postpubertal period.
Ocular: Loss of eyebrow; loss of eyelashes; central scotomata; diabetic retinopathy tends to improve after development of this syndrome; optic nerve atrophy (descending type).
Clinical: Weight loss and generalized weakness (progressive); anorexia; amenorrhea; dry skin and brittle nails; hypotension with bradycardia; anemia; psychosis; loss of libido.
Blondell RD. Hypopituitarism. Am Fam Physician 1991; 43:2029-2936.
Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.
Simmonds M. Uber Hypophysisschwund mit Todlichem Ausgang. Dtsch Med Wochenschr 1914; 40:322.
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