Toxic lens syndrome ( toxic anterior segment syndrome; tass) 1

General: Syndrome occurs within a few days to several weeks of imtation of an intraocular lens; with t 525e45f herapy, vision is restored in the majority of cases; increased incidence of disease caused by use of ethylene oxide sterilization (dry pack intraocular lenses); toxic lens syndrome may be prevented by treating the lens with sodium hydroxide and by using modem lathe-cut or compression-molded lenses with polypropylene loops; risk factors include uveitis in history, pseudoexfoliation syndrome, inadequate mydriasis at the start of surgery, problems with intraocular lens imtation, and pigment effusion during surgery.

Ocular: Pigment precipitation on the surface of an intraocular lens; hypopyon; vitreous opacification; chronic uveitis; secondary glaucoma.

Clinical: None.

Alpar JJ. Toxic lens syndrome. J Ocul Ther Surg 1982; 5:306-308.

Drolsum L et al. Risk factors for an inflammatory response after extracapsular cataract extraction and posterior chamber IOL. Acta Ophthalmol 1994; 72:21-26.

Hellinger Wc, Hasan SA, Bacalis LP, et al. Outbreak of toxic anterior segment syndrome following cataract surgery associated with impurities in autoclave steam moisture. Infect Control Hosp Epidemiol 2006; 27: 294-2

Mamalis, N, Edelhauser HF, Dawson DG, et al. Toxic anterior segment syndrome. J Cataract Refract Surg 2006; 32: 324-

Werner,L, Sher JH, Taylor JR, et al. Toxic anterior segment syndrome and possible association with ointment in the anterior chamber following cataract surgery. J Cataract Refract Surg 2006; 32: 227-