Tropical Pancreatic Diabetes (TPD)
General: Secondary diabetes as a 121b12b result of chronic calcific pancreatitis; limited geographically to a few tropical countries; highest prevalence in southern India; male predominance; onset at young age; associated with protein calorie malnutrition; possible cause is cassava ingestion; malnutrition has been postulated as a possible etiology.
Ocular: Background retinopathy; proliferative retinopathy; fibrous retinitis proliferans; microaneurysms; macular edema; hemorrhages; exudates; decreased visual acuity.
Clinical: Chronic pancreatitis; recurrent abdominal pain; steatorrhea.
Jarrett RJ, Keen H. Hyperglycemia and diabetic mellitus. Lancet 1976; 2: 1009-l112.
Mohan R, et al. Retinopathy in tropical pancreatic diabetes. Arch Ophthalmol 1986; 103:1487-l489.
Rao RH. Is tropical pancreatic diabetes malnutrition related? Diabetes Care 1993; 16:941-945.
Thomas SV, et al. Visual evoked potential changes in patients with tropical pancreatic diabetes. Acta Neurol 1993; 15:427-432.
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