WEBINO Syndrome (Wall-Eyed Bilateral Internuclear Ophthalmoplegia) 1
General: Differential diagnosis includes demyelinating disease, arteriosclerotic cerebrovascular 111e49b disease, trauma, Arnold-Chiari malformation, syphilis, periarteritis nodosa, glioma, cryptococcal meningitis, and premature infants; usually represents midline involvement of oculomotor nucleus.
Ocular: Wall-eyed internuclear ophthalmoplegia (bilateral internuclear ophthalmoplegia with exotropia).
Clinical: Depends on cause; association with multiple sclerosis in young patients.
Daroff RE, Hoyt WE Supranuclear disorders of ocular control systems in man. In: Bach-Y-Rita P, Collins CC, eds. The control of eye movements. Orlando, FL: Academic Press, 1971:223.
Lepore FE, Nissenblatt MJ. Bilateral internuclear ophthalmoplegia after intrathecal chemotherapy and cranial irradiation. Am J Ophthalmol 1981; 92:851-853.
Miller NR, ed. Walsh and Hoyts Clinical Neuro-Ophthalmology, vol. 5, part 1, 4th ed. Baltimore: Williams & Wilkins, 1995:4323.
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