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Aminopterin-induced syndrome


Aminopterin-Induced Syndrome 737e45h 737e45h 737e45h 737e45h 737e45h

General: Teratogenic effect of aminopterin and derivatives on fetus; present at birth; usually fetal or postnatal death.

Ocular: Hypertelorism.

Clinical: Small body; microcephaly; hypoplasia of cranial bones; broad nasal bridge; micrognathia; cleft palate; low-set ears; mesomelic; hypodactyly; talipes equinovarus.

Magalini SI, Scrascia E. Dictionary of Medical Syndromes, 2nd ed. Philadelphia: JB Lippincott, 1981.

Shaw EB, Steinbach HL. Aminopterin-induced fetal malformation. Am J Dis Child





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