Peters anomaly

General: Autosomal recessive; may be mo 757g68h rphologic entity with several eye syndromes, including Rieger syndrome, Mietens syndrome, and fetal alcohol syndrome; may be due to a developmental field defect, a contiguous gene syndrome, or a defective homeotic gene controlling development of the eye and other body structures.

Ocular: Corneal opacification; lenticulocorneal adherence; iris adhesions; glaucoma; cataract; narrow lid fissures; colobomatous microphthalmia; persistent hyperplastic primary vitreous; retinal detachment; iris nodules.

Clinical: Short-limbed dwarfism; broad face; thin upper lip; hypoplastic columnella; hypospadias; cleft lip and palate; craniofacial abnormalities; congenital heart disease; horseshoe kidney; polycystic kidneys; Wilms tumor; mental retardation; external ear anomalies; camptodactyly.

Bateman FB, et al. Peters' anomaly associated with partial deletion of the long arm of chromosome 11. Am J Ophthalmol 1984; 98:11-l5.

Heon E, et al. Peters' anomaly. The spectrum of associated ocular and systemic malformations. Ophthalmic Paediatr Genet 1992; 13:137-l43.

Kivlin JD, et al. Peters' anomaly as a consequence of genetic and nongenetic syndrome. Arch Ophthalmol 1986; 104: 61-64.

Peters A. Ueber Angeborene Defektbildung der Descemetshem Membrane. Klin Monatsbl Augenheilkd 1906; 44: 27-41.

Pillay VK. Ophthalmolo-mandibulo-melic dysplasia. J Bone Joint Surg Am 1964; 46:858-862.

Traboulsi EI, Maumenee IH. Peters' anomaly and associated congenital malformations. Arch Ophthalmol 1992; 110: 1739-l742.